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The Effect of Losartan on Neuroinflammation as Well as on Endothelin-1- and Serotonin-Induced Vasoconstriction in a Double-Haemorrhage Rat Model
Poor patient outcome after aneurysmal subarachnoid haemorrhage (SAH) is due to a multifactorial process. Delayed cerebral vasospasm, ischemic neurological deficits, and infarction are the most feared acute sequelae triggered by enhanced synthesis of serotonin and endothelin-1 (ET-1). During the past...
Autores principales: | Konczalla, Jürgen, Mrosek, Jan, Kashefiolasl, Sepide, Musahl, Christian, Marbacher, Serge, Schubert, Gerrit Alexander, Andereggen, Lukas, Wanderer, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785729/ https://www.ncbi.nlm.nih.gov/pubmed/36555984 http://dx.doi.org/10.3390/jcm11247367 |
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