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Aromatase-Inhibitor-Induced Musculoskeletal Inflammation Is Observed Independent of Oophorectomy in a Novel Mouse Model

Aromatase Inhibitors (AIs) block estrogen production and improve survival in patients with hormone-receptor-positive breast cancer. However, half of patients develop aromatase-inhibitor-induced arthralgia (AIIA), which is characterized by inflammation of the joints and the surrounding musculoskeleta...

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Detalles Bibliográficos
Autores principales: Young, Nicholas A., Hampton, Jeffrey, Sharma, Juhi, Jablonski, Kyle, DeVries, Courtney, Bratasz, Anna, Wu, Lai-Chu, Lustberg, Maryam, Reinbolt, Raquel, Jarjour, Wael N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785754/
https://www.ncbi.nlm.nih.gov/pubmed/36559029
http://dx.doi.org/10.3390/ph15121578