Lipidation of NOD2 Agonists with Adamantane and Stearoyl Moieties Differentially Regulates Their In Vivo Adjuvant Activity

NOD2 is an innate immune receptor that constitutes an important target for the development of small molecule immunopotentiators with great potential to be used as vaccine adjuvants. We report here the results of an in vivo study of the adjuvant properties of a desmuramylpeptide NOD2 agonist SG29 and...

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Detalles Bibliográficos
Autores principales: Guzelj, Samo, Šišić, Marcela, Bizjak, Špela, Frkanec, Leo, Frkanec, Ruža, Jakopin, Žiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785857/
https://www.ncbi.nlm.nih.gov/pubmed/36559249
http://dx.doi.org/10.3390/pharmaceutics14122755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785857/
https://www.ncbi.nlm.nih.gov/pubmed/36559249
http://dx.doi.org/10.3390/pharmaceutics14122755

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