(-)-Epigallocatechin-3-gallate Directly Binds Cyclophilin D: A Potential Mechanism for Mitochondrial Protection

(1) Background: (-)-Epigallocatechin-3-gallate (EGCG) has been reported to improve mitochondrial function in cell models, while the underlying mechanism is not clear. Cyclophilin D (CypD) is a key protein that regulates mitochondrial permeability transition pore (mPTP) opening. (2) Methods: In this...

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Detalles Bibliográficos
Autores principales: Wu, Annan, Zhang, Jie, Li, Quanhong, Liao, Xiaojun, Wang, Chunyu, Zhao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785876/
https://www.ncbi.nlm.nih.gov/pubmed/36557795
http://dx.doi.org/10.3390/molecules27248661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785876/
https://www.ncbi.nlm.nih.gov/pubmed/36557795
http://dx.doi.org/10.3390/molecules27248661

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