Evaluation of the Association between Single Nucleotide Polymorphisms of Metabolizing Enzymes with the Serum Concentration of Paracetamol and Its Metabolites

Intravenous paracetamol is a commonly administered analgesic and antipyretic in inpatient settings. Paracetamol is metabolized by cytochrome P450 (CYP) enzymes followed by conjugating enzymes to mainly glucuronide but to a lesser extent, sulphate metabolites, and oxidative metabolites. Single nucleo...

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Detalles Bibliográficos
Autores principales: Sridharan, Kannan, Qader, Ali Mohamed, Hammad, Mustafa, Jassim, Anfal, Diab, Diab Eltayeb, Abraham, Betsy, Hasan, Hasan M. S. N., Pasha, Sheikh Abdul Azeez, Shah, Shamik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785892/
https://www.ncbi.nlm.nih.gov/pubmed/36557273
http://dx.doi.org/10.3390/metabo12121235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785892/
https://www.ncbi.nlm.nih.gov/pubmed/36557273
http://dx.doi.org/10.3390/metabo12121235

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