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Synthesis and Anti-Tumor Effects of Novel Pomalidomide Derivatives Containing Urea Moieties

In order to explore novel immunomodulatory agents as anti-tumor drugs, we designed and synthesized a series of new pomalidomide derivatives containing urea moieties. Interestingly, in vitro biological experiments performed in several cancer cell lines showed that some of them displayed potent anti-t...

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Detalles Bibliográficos
Autores principales: Guo, Yajie, Wang, Xi, Wang, Zhenzhen, Mao, Longfei, Wang, Jiahao, Peng, Lizeng, Xu, Guiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785895/
https://www.ncbi.nlm.nih.gov/pubmed/36558930
http://dx.doi.org/10.3390/ph15121479