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Synthesis and Anti-Tumor Effects of Novel Pomalidomide Derivatives Containing Urea Moieties
In order to explore novel immunomodulatory agents as anti-tumor drugs, we designed and synthesized a series of new pomalidomide derivatives containing urea moieties. Interestingly, in vitro biological experiments performed in several cancer cell lines showed that some of them displayed potent anti-t...
Autores principales: | Guo, Yajie, Wang, Xi, Wang, Zhenzhen, Mao, Longfei, Wang, Jiahao, Peng, Lizeng, Xu, Guiqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785895/ https://www.ncbi.nlm.nih.gov/pubmed/36558930 http://dx.doi.org/10.3390/ph15121479 |
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