Self-Assembled TLR7/8 Agonist-Mannose Conjugate as An Effective Vaccine Adjuvant for SARS-CoV-2 RBD Trimer

Small synthetic TLR7/8-agonists can be used as vaccine adjuvants to enhance cell and humoral-mediated immune responses to specific antigens. Despite their potency, after local injection they can be dispersed to undesired body parts causing high reactogenicity, limiting their clinical applications. H...

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Detalles Bibliográficos
Autores principales: Teng, Changcai, Meng, Xiongyan, Hu, Yeqin, Mao, Hongzhao, Li, Huiting, Yang, Jing, Sun, Tiantian, Meng, Shuai, Zong, Chengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785909/
https://www.ncbi.nlm.nih.gov/pubmed/36559833
http://dx.doi.org/10.3390/polym14245466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785909/
https://www.ncbi.nlm.nih.gov/pubmed/36559833
http://dx.doi.org/10.3390/polym14245466

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