Cargando…

Nuclear S6K1 Enhances Oncogenic Wnt Signaling by Inducing Wnt/β-Catenin Transcriptional Complex Formation

Ribosomal protein S6 kinase 1 (S6K1), a key downstream effector of the mammalian target of rapamycin (mTOR), regulates diverse functions, such as cell proliferation, cell growth, and protein synthesis. Because S6K1 was previously known to be localized in the cytoplasm, its function has been mainly s...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Min Gyu, Oh, Hwamok, Park, Jong Woo, You, Jueng Soo, Han, Jeung-Whan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785994/
https://www.ncbi.nlm.nih.gov/pubmed/36555784
http://dx.doi.org/10.3390/ijms232416143