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Nuclear S6K1 Enhances Oncogenic Wnt Signaling by Inducing Wnt/β-Catenin Transcriptional Complex Formation
Ribosomal protein S6 kinase 1 (S6K1), a key downstream effector of the mammalian target of rapamycin (mTOR), regulates diverse functions, such as cell proliferation, cell growth, and protein synthesis. Because S6K1 was previously known to be localized in the cytoplasm, its function has been mainly s...
Autores principales: | Lee, Min Gyu, Oh, Hwamok, Park, Jong Woo, You, Jueng Soo, Han, Jeung-Whan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785994/ https://www.ncbi.nlm.nih.gov/pubmed/36555784 http://dx.doi.org/10.3390/ijms232416143 |
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