Functional Diversification of Oyster Big Defensins Generates Antimicrobial Specificity and Synergy against Members of the Microbiota

Big defensins are two-domain antimicrobial peptides (AMPs) that have highly diversified in mollusks. Cg-BigDefs are expressed by immune cells in the oyster Crassostrea gigas, and their expression is dampened during the Pacific Oyster Mortality Syndrome (POMS), which evolves toward fatal bacteremia....

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Detalles Bibliográficos
Autores principales: De San Nicolas, Noémie, Asokan, Aromal, Rosa, Rafael D., Voisin, Sébastien N., Travers, Marie-Agnès, Rocha, Gustavo, Dantan, Luc, Dorant, Yann, Mitta, Guillaume, Petton, Bruno, Charrière, Guillaume M., Escoubas, Jean-Michel, Boulo, Viviane, Pouzadoux, Juliette, Meudal, Hervé, Loth, Karine, Aucagne, Vincent, Delmas, Agnès F., Bulet, Philippe, Montagnani, Caroline, Destoumieux-Garzón, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786018/
https://www.ncbi.nlm.nih.gov/pubmed/36547892
http://dx.doi.org/10.3390/md20120745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786018/
https://www.ncbi.nlm.nih.gov/pubmed/36547892
http://dx.doi.org/10.3390/md20120745

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