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Natural Product 2-Oxokolavenol Is a Novel FXR Agonist

Acetaminophen (APAP) toxicity is a common cause of hepatic failure, and the development of effective therapy is still urgently needed. Farnesoid X receptor (FXR), a member of the nuclear receptor superfamily, has been identified as a master gene for regulating enterohepatic metabolic homeostasis and...

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Detalles Bibliográficos
Autores principales: Guo, Fusheng, Gao, Yihui, Li, Xiaobao, Lei, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786051/
https://www.ncbi.nlm.nih.gov/pubmed/36558100
http://dx.doi.org/10.3390/molecules27248968