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Natural Product 2-Oxokolavenol Is a Novel FXR Agonist
Acetaminophen (APAP) toxicity is a common cause of hepatic failure, and the development of effective therapy is still urgently needed. Farnesoid X receptor (FXR), a member of the nuclear receptor superfamily, has been identified as a master gene for regulating enterohepatic metabolic homeostasis and...
Autores principales: | Guo, Fusheng, Gao, Yihui, Li, Xiaobao, Lei, Xiaoguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786051/ https://www.ncbi.nlm.nih.gov/pubmed/36558100 http://dx.doi.org/10.3390/molecules27248968 |
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