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Potent and Selective Inhibition of CYP1A2 Enzyme by Obtusifolin and Its Chemopreventive Effects

Obtusifolin, a major anthraquinone component present in the seeds of Cassia tora, exhibits several biological activities, including the amelioration of memory impairment, prevention of breast cancer metastasis, and reduction of cartilage damage in osteoarthritis. We aimed to evaluate the inhibitory...

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Detalles Bibliográficos
Autores principales: Park, Eun-Ji, Park, Keunwan, Durai, Prasannavenkatesh, Kim, Ki-Young, Park, So-Young, Kwon, Jaeyoung, Lee, Hee Ju, Pan, Cheol-Ho, Liu, Kwang-Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786103/
https://www.ncbi.nlm.nih.gov/pubmed/36559174
http://dx.doi.org/10.3390/pharmaceutics14122683