Inhibition of TIGAR Increases Exogenous p53 and Cisplatin Combination Sensitivity in Lung Cancer Cells by Regulating Glycolytic Flux

The metabolism and apoptosis of tumor cells are important factors that increase their sensitivity to chemotherapeutic drugs. p53 and cisplatin not only induce tumor cell apoptosis, but also regulate the tumor cell metabolism. The TP53-induced glycolysis and apoptosis regulator (TIGAR) can inhibit gl...

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Detalles Bibliográficos
Autores principales: Fu, Jiaying, Yu, Sihang, Zhao, Xiyao, Zhang, Chaoke, Shen, Luyan, Liu, Yanan, Yu, Huimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786130/
https://www.ncbi.nlm.nih.gov/pubmed/36555672
http://dx.doi.org/10.3390/ijms232416034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786130/
https://www.ncbi.nlm.nih.gov/pubmed/36555672
http://dx.doi.org/10.3390/ijms232416034

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