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Short-Chain Fatty Acids Weaken Ox-LDL-Induced Cell Inflammatory Injury by Inhibiting the NLRP3/Caspase-1 Pathway and Affecting Cellular Metabolism in THP-1 Cells

Short-chain fatty acids (SCFAs) are important anti-inflammatory metabolites of intestinal flora. Oxidized low-density lipoprotein (ox-LDL)-induced macrophage activation is critical for the formation of atherosclerosis plaque. However, the association between SCFAs and ox-LDL-induced macrophage activ...

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Detalles Bibliográficos
Autores principales: Yi, Chengxue, Sun, Wen, Ding, Longkun, Yan, Man, Sun, Chang, Qiu, Chenguang, Wang, Dongxu, Wu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786193/
https://www.ncbi.nlm.nih.gov/pubmed/36557935
http://dx.doi.org/10.3390/molecules27248801