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Application of a Human Blood Brain Barrier Organ-on-a-Chip Model to Evaluate Small Molecule Effectiveness against Venezuelan Equine Encephalitis Virus

The blood brain barrier (BBB) is a multicellular microenvironment that plays an important role in regulating bidirectional transport to and from the central nervous system (CNS). Infections by many acutely infectious viruses such as alphaviruses and flaviviruses are known to impact the integrity of...

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Detalles Bibliográficos
Autores principales: Boghdeh, Niloufar A., Risner, Kenneth H., Barrera, Michael D., Britt, Clayton M., Schaffer, David K., Alem, Farhang, Brown, Jacquelyn A., Wikswo, John P., Narayanan, Aarthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786295/
https://www.ncbi.nlm.nih.gov/pubmed/36560802
http://dx.doi.org/10.3390/v14122799