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Polyester Nanocapsules for Intravenous Delivery of Artemether: Formulation Development, Antimalarial Efficacy, and Cardioprotective Effects In Vivo

Artemether (ATM) is an effective antimalarial drug that also has a short half-life in the blood. Furthermore, ATM is also cardiotoxic and is associated with pro-arrhythmogenic risks. We aimed to develop a delivery system enabling the prolonged release of ATM into the blood coupled with reduced cardi...

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Detalles Bibliográficos
Autores principales: Vidal-Diniz, Alessandra Teixeira, Guimarães, Homero Nogueira, Garcia, Giani Martins, Braga, Érika Martins, Richard, Sylvain, Grabe-Guimarães, Andrea, Mosqueira, Vanessa Carla Furtado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786304/
https://www.ncbi.nlm.nih.gov/pubmed/36559869
http://dx.doi.org/10.3390/polym14245503