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Polyester Nanocapsules for Intravenous Delivery of Artemether: Formulation Development, Antimalarial Efficacy, and Cardioprotective Effects In Vivo
Artemether (ATM) is an effective antimalarial drug that also has a short half-life in the blood. Furthermore, ATM is also cardiotoxic and is associated with pro-arrhythmogenic risks. We aimed to develop a delivery system enabling the prolonged release of ATM into the blood coupled with reduced cardi...
Autores principales: | Vidal-Diniz, Alessandra Teixeira, Guimarães, Homero Nogueira, Garcia, Giani Martins, Braga, Érika Martins, Richard, Sylvain, Grabe-Guimarães, Andrea, Mosqueira, Vanessa Carla Furtado |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786304/ https://www.ncbi.nlm.nih.gov/pubmed/36559869 http://dx.doi.org/10.3390/polym14245503 |
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