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IFN-α/β Signaling Is Required for CDG-Mediated CTL Generation and B Lymphocyte Activation
Among cyclic di-nucleotides (CDN), both cyclic di-AMP (CDA) and di-GMP (CDG) are promising adjuvants and immune modulators. These molecules are not only able to induce profuse antibody production but also predominant T helper 1 and cytotoxic CD8 T lymphocytes (CTL) responses, which enable their use...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786310/ https://www.ncbi.nlm.nih.gov/pubmed/36559314 http://dx.doi.org/10.3390/pharmaceutics14122821 |