Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer

The Hedgehog signaling pathway functions in both embryonic development and adult tissue homeostasis. Importantly, its aberrant activation is also implicated in the progression of multiple types of cancer, including basal cell carcinoma and medulloblastoma. GLI transcription factors function as the u...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Wynn, Daniel T., Shen, Chen, Ayad, Nagi G., Robbins, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786339/
https://www.ncbi.nlm.nih.gov/pubmed/36556332
http://dx.doi.org/10.3390/life12121967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786339/
https://www.ncbi.nlm.nih.gov/pubmed/36556332
http://dx.doi.org/10.3390/life12121967

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