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Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer
The Hedgehog signaling pathway functions in both embryonic development and adult tissue homeostasis. Importantly, its aberrant activation is also implicated in the progression of multiple types of cancer, including basal cell carcinoma and medulloblastoma. GLI transcription factors function as the u...
Autores principales: | Yang, Fan, Wynn, Daniel T., Shen, Chen, Ayad, Nagi G., Robbins, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786339/ https://www.ncbi.nlm.nih.gov/pubmed/36556332 http://dx.doi.org/10.3390/life12121967 |
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