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Fingolimod effects on the brain are mediated through biochemical modulation of bioenergetics, autophagy, and neuroinflammatory networks

Fingolimod (FTY720) is an oral drug approved by the Food and Drug Administration (FDA) for management of multiple sclerosis (MS) symptoms, which has also shown beneficial effects against Alzheimer's (AD) and Parkinson's (PD) diseases pathologies. Although an extensive effort has been made...

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Detalles Bibliográficos
Autores principales: Mirzaei, Mehdi, Abyadeh, Morteza, Turner, Anita J., Wall, Roshana Vander, Chick, Joel M., Paulo, Joao A., Gupta, Veer K., Basavarajappa, Devaraj, Chitranshi, Nitin, Mirshahvaladi, Seyed Shahab Oddin, You, Yuyi, Fitzhenry, Matthew J., Amirkhani, Ardeshir, Haynes, Paul A., Klistorner, Alexander, Gupta, Vivek, Graham, Stuart L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786555/
https://www.ncbi.nlm.nih.gov/pubmed/35866514
http://dx.doi.org/10.1002/pmic.202100247