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Tailoring the AIE Chromogen 2-(2-Hydroxyphenyl)benzothiazole for Use in Enzyme-Triggered Molecular Brachytherapy

A targeted strategy for treating cancer is antibody-directed enzyme prodrug therapy, where the enzyme attached to the antibody causes conversion of an inactive small-molecule prodrug into an active drug. A limitation may be the diffusion of the active drug away from the antibody target site. A relat...

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Detalles Bibliográficos
Autores principales: Wu, Zhiyuan, Dou, Jinghuai, Nguyen, Kathy-Uyen, Eppley, Jayden C., Siwawannapong, Kittipan, Zhang, Yunlong, Lindsey, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786593/
https://www.ncbi.nlm.nih.gov/pubmed/36557815
http://dx.doi.org/10.3390/molecules27248682