APP accumulates with presynaptic proteins around amyloid plaques: A role for presynaptic mechanisms in Alzheimer's disease?

In Alzheimer's disease (AD), the distribution of the amyloid precursor protein (APP) and its fragments other than amyloid beta, has not been fully characterized. Here, we investigate the distribution of APP and its fragments in human AD brain samples and in mouse models of AD in reference to it...

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Detalles Bibliográficos
Autores principales: Jordà‐Siquier, Tomàs, Petrel, Melina, Kouskoff, Vladimir, Smailovic, Una, Cordelières, Fabrice, Frykman, Susanne, Müller, Ulrike, Mulle, Christophe, Barthet, Gaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786597/
https://www.ncbi.nlm.nih.gov/pubmed/35076178
http://dx.doi.org/10.1002/alz.12546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786597/
https://www.ncbi.nlm.nih.gov/pubmed/35076178
http://dx.doi.org/10.1002/alz.12546

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