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Nerve Targeting via Myelin Protein Zero and the Impact of Dimerization on Binding Affinity

Background: Surgically induced nerve damage is a common but debilitating side effect. By developing tracers that specifically target the most abundant protein in peripheral myelin, namely myelin protein zero (P0), we intend to support fluorescence-guided nerve-sparing surgery. To that end, we aimed...

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Detalles Bibliográficos
Autores principales: Berehova, Nataliia, Buckle, Tessa, van Meerbeek, Maarten P., Bunschoten, Anton, Velders, Aldrik H., van Leeuwen, Fijs W. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786614/
https://www.ncbi.nlm.nih.gov/pubmed/36558148
http://dx.doi.org/10.3390/molecules27249015