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Fecal luminal factors from patients with irritable bowel syndrome induce distinct gene expression of colonoids

BACKGROUND: Alteration of the host‐microbiota cross talk at the intestinal barrier may participate in the pathophysiology of irritable bowel syndrome (IBS). Therefore, we aimed to determine effects of fecal luminal factors from IBS patients on the colonic epithelium using colonoids. METHODS: Colon‐d...

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Bibliographic Details
Main Authors: Iribarren, Cristina, Nordlander, Sofia, Sundin, Johanna, Isaksson, Stefan, Savolainen, Otto, Törnblom, Hans, Magnusson, Maria K., Simrén, Magnus, Öhman, Lena
Format: Online Article Text
Language:English
Published: John Wiley and Sons Inc. 2022
Subjects:
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786662/
https://www.ncbi.nlm.nih.gov/pubmed/35485994
http://dx.doi.org/10.1111/nmo.14390