Transcriptomic Analysis of the Acute Skeletal Muscle Effects after Intramuscular DNA Electroporation Reveals Inflammatory Signaling

Skeletal muscle is a promising tissue for therapeutic gene delivery because it is highly vascularized, accessible, and capable of synthesizing protein for therapies or vaccines. The application of electric pulses (electroporation) enhances plasmid DNA delivery and expression by increasing membrane p...

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Detalles Bibliográficos
Autores principales: Sales Conniff, Amanda, Tur, Jared, Kohena, Kristopher, Zhang, Min, Gibbons, Justin, Heller, Loree C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786673/
https://www.ncbi.nlm.nih.gov/pubmed/36560447
http://dx.doi.org/10.3390/vaccines10122037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786673/
https://www.ncbi.nlm.nih.gov/pubmed/36560447
http://dx.doi.org/10.3390/vaccines10122037

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