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Transcriptomic Analysis of the Acute Skeletal Muscle Effects after Intramuscular DNA Electroporation Reveals Inflammatory Signaling
Skeletal muscle is a promising tissue for therapeutic gene delivery because it is highly vascularized, accessible, and capable of synthesizing protein for therapies or vaccines. The application of electric pulses (electroporation) enhances plasmid DNA delivery and expression by increasing membrane p...
Autores principales: | Sales Conniff, Amanda, Tur, Jared, Kohena, Kristopher, Zhang, Min, Gibbons, Justin, Heller, Loree C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786673/ https://www.ncbi.nlm.nih.gov/pubmed/36560447 http://dx.doi.org/10.3390/vaccines10122037 |
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