Cargando…

Indoleamine 2,3‐dioxygenase 1 (IDO1): an up‐to‐date overview of an eclectic immunoregulatory enzyme

Indoleamine 2,3‐dioxygenase 1 (IDO1) catalyzes the initial rate‐limiting step in the degradation of the essential amino acid tryptophan along the kynurenine pathway. When discovered more than 50 years ago, IDO1 was thought to be an effector molecule capable of mediating a survival strategy based on...

Descripción completa

Detalles Bibliográficos
Autores principales: Pallotta, Maria Teresa, Rossini, Sofia, Suvieri, Chiara, Coletti, Alice, Orabona, Ciriana, Macchiarulo, Antonio, Volpi, Claudia, Grohmann, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786828/
https://www.ncbi.nlm.nih.gov/pubmed/34145969
http://dx.doi.org/10.1111/febs.16086