In Silico Study of the Interactions of Anle138b Isomer, an Inhibitor of Amyloid Aggregation, with Partner Proteins

Herein, we aimed to highlight current “gaps” in the understanding of the potential interactions between the Anle138b isomer ligand, a promising agent for clinical research, and the intrinsically disordered alpha-synuclein protein. The presence of extensive unstructured areas in alpha-synuclein deter...

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Detalles Bibliográficos
Autores principales: Kondratyev, Maxim S., Rudnev, Vladimir R., Nikolsky, Kirill S., Petrovsky, Denis V., Kulikova, Liudmila I., Malsagova, Kristina A., Stepanov, Alexander A., Kopylov, Arthur T., Kaysheva, Anna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786835/
https://www.ncbi.nlm.nih.gov/pubmed/36555748
http://dx.doi.org/10.3390/ijms232416096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786835/
https://www.ncbi.nlm.nih.gov/pubmed/36555748
http://dx.doi.org/10.3390/ijms232416096

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