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In Silico Study of the Interactions of Anle138b Isomer, an Inhibitor of Amyloid Aggregation, with Partner Proteins
Herein, we aimed to highlight current “gaps” in the understanding of the potential interactions between the Anle138b isomer ligand, a promising agent for clinical research, and the intrinsically disordered alpha-synuclein protein. The presence of extensive unstructured areas in alpha-synuclein deter...
Autores principales: | Kondratyev, Maxim S., Rudnev, Vladimir R., Nikolsky, Kirill S., Petrovsky, Denis V., Kulikova, Liudmila I., Malsagova, Kristina A., Stepanov, Alexander A., Kopylov, Arthur T., Kaysheva, Anna L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786835/ https://www.ncbi.nlm.nih.gov/pubmed/36555748 http://dx.doi.org/10.3390/ijms232416096 |
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