APOE ε2 resilience for Alzheimer's disease is mediated by plasma lipid species: Analysis of three independent cohort studies

INTRODUCTION: The apolipoprotein E (APOE) genotype is the strongest genetic risk factor for late‐onset Alzheimer's disease. However, its effect on lipid metabolic pathways, and their mediating effect on disease risk, is poorly understood. METHODS: We performed lipidomic analysis on three indepe...

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Detalles Bibliográficos
Autores principales: Wang, Tingting, Huynh, Kevin, Giles, Corey, Mellett, Natalie A, Duong, Thy, Nguyen, Anh, Lim, Wei Ling Florence, Smith, Alex AT, Olshansky, Gavriel, Cadby, Gemma, Hung, Joseph, Hui, Jennie, Beilby, John, Watts, Gerald F, Chatterjee, Pratishtha, Martins, Ian, Laws, Simon M, Bush, Ashley I, Rowe, Christopher C, Villemagne, Victor L, Ames, David, Masters, Colin L, Taddei, Kevin, Doré, Vincent, Fripp, Jürgen, Arnold, Matthias, Kastenmüller, Gabi, Nho, Kwangsik, Saykin, Andrew J, Baillie, Rebecca, Han, Xianlin, Martins, Ralph N, Moses, Eric K, Kaddurah‐Daouk, Rima, Meikle, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787288/
https://www.ncbi.nlm.nih.gov/pubmed/35077012
http://dx.doi.org/10.1002/alz.12538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787288/
https://www.ncbi.nlm.nih.gov/pubmed/35077012
http://dx.doi.org/10.1002/alz.12538

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