Nanoparticle-Delivered Transforming Growth Factor-β1 siRNA Induces PD-1 against Gastric Cancer by Transforming the Phenotype of the Tumor Immune Microenvironment

Immune checkpoint blockade (ICB) is currently considered to be an important therapeutic method, which obtained FDA approval for clinical use in gastric cancer in 2017. As a new mechanism, it was found that the effect of αPDL1 could be improved by blocking the TGF-β1 signaling pathway, which converts...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Fenglei, Xu, Xiujuan, Li, Wei, Hong, Yidong, Lai, Huan, Zhang, Jingzhou, Wu, Xueyu, Zhou, Kangjie, Hu, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787292/
https://www.ncbi.nlm.nih.gov/pubmed/36558938
http://dx.doi.org/10.3390/ph15121487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787292/
https://www.ncbi.nlm.nih.gov/pubmed/36558938
http://dx.doi.org/10.3390/ph15121487

Ejemplares similares