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Gene Editing Technologies to Target HBV cccDNA

Hepatitis B virus (HBV) remains a significant cause of mortality and morbidity worldwide, since chronic HBV infection is associated with elevated risk of cirrhosis and hepatocellular carcinoma. Current licensed therapies against HBV efficiently suppress viral replication; however, they do not have s...

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Detalles Bibliográficos
Autores principales: Martinez, Maria Guadalupe, Smekalova, Elena, Combe, Emmanuel, Gregoire, Francine, Zoulim, Fabien, Testoni, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787400/
https://www.ncbi.nlm.nih.gov/pubmed/36560658
http://dx.doi.org/10.3390/v14122654