Ranpirnase (OKG-0301), a Novel Ribonuclease, Demonstrates Antiviral Activity against Adenovirus in the Ad5/NZW Rabbit Ocular Replication Model

Adenovirus ocular infections are common ocular viral infections seen worldwide, for which there is no approved antiviral therapy available. Ranpirnase is a novel ribonuclease which preferentially degrades tRNA resulting in an inhibition of protein synthesis. The study goal was to determine the anti-...

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Detalles Bibliográficos
Autores principales: Romanowski, Eric G., Yates, Kathleen A., Daniels, Eric J., Strem, Brian M., Romanowski, John E., Kowalski, Regis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787402/
https://www.ncbi.nlm.nih.gov/pubmed/36558819
http://dx.doi.org/10.3390/pathogens11121485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787402/
https://www.ncbi.nlm.nih.gov/pubmed/36558819
http://dx.doi.org/10.3390/pathogens11121485

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