Impact of Albumin Binding Function on Pharmacokinetics and Pharmacodynamics of Furosemide

Background and Objectives: Albumin binding of the loop diuretic furosemide forms the basis for its transport to the kidney and subsequent tubular secretion, which is a prerequisite for its therapeutic effects. Accordingly, high albumin concentrations should result in higher efficacy of furosemide. H...

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Detalles Bibliográficos
Autores principales: Klinkmann, Gerd, Klammt, Sebastian, Jäschke, Malte, Henschel, Jörg, Gloger, Martin, Reuter, Daniel A., Mitzner, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787406/
https://www.ncbi.nlm.nih.gov/pubmed/36556982
http://dx.doi.org/10.3390/medicina58121780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787406/
https://www.ncbi.nlm.nih.gov/pubmed/36556982
http://dx.doi.org/10.3390/medicina58121780

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