Cancer Cachexia and Dysregulated Phosphate Metabolism: Insights from Mutant p53 and Mutant Klotho Mouse Models

The present perspective article proposes that cachexia, muscle wasting in cancer, is mediated by dysregulated phosphate metabolism and phosphate toxicity that can damage tissues in most major organ systems. A diet high in phosphorus fed to mice deficient in klotho, a cofactor that regulates phosphat...

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Detalles Bibliográficos
Autor principal: Brown, Ronald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787668/
https://www.ncbi.nlm.nih.gov/pubmed/36557322
http://dx.doi.org/10.3390/metabo12121284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787668/
https://www.ncbi.nlm.nih.gov/pubmed/36557322
http://dx.doi.org/10.3390/metabo12121284

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