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Model of severe malaria in young mice suggests unique response of CD4 T cells

Severe malaria occurs most in young children but is poorly understood due to the absence of a developmentally‐equivalent rodent model to study the pathogenesis of the disease. Though functional and quantitative deficiencies in innate response and a biased T helper 1 (Th1) response are reported in ne...

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Detalles Bibliográficos
Autores principales: Smith, Margaret R., Gbedande, Komi, Johnson, Corey M., Campbell, Logan A., Onjiko, Robert S., Domingo, Nadia D., Opata, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787679/
https://www.ncbi.nlm.nih.gov/pubmed/36131528
http://dx.doi.org/10.1111/pim.12952