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Harmine Inhibits Multiple TLR-Induced Inflammatory Expression through Modulation of NF-κB p65, JNK, and STAT1

Harmine is a beta-carboline alkaloid present in various plants, including in the seeds of Peganum harmala L. This study aimed to investigate the anti-inflammatory activity and mechanism of harmine using macrophages stimulated with various toll-like receptor (TLR) agonists and a model of endotoxemia....

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Detalles Bibliográficos
Autores principales: Jin, So-Jung, Song, Youngju, Park, Hong Shik, Park, Kye Won, Lee, SeungGwan, Kang, Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787735/
https://www.ncbi.nlm.nih.gov/pubmed/36556387
http://dx.doi.org/10.3390/life12122022