Cargando…
Harmine Inhibits Multiple TLR-Induced Inflammatory Expression through Modulation of NF-κB p65, JNK, and STAT1
Harmine is a beta-carboline alkaloid present in various plants, including in the seeds of Peganum harmala L. This study aimed to investigate the anti-inflammatory activity and mechanism of harmine using macrophages stimulated with various toll-like receptor (TLR) agonists and a model of endotoxemia....
Autores principales: | Jin, So-Jung, Song, Youngju, Park, Hong Shik, Park, Kye Won, Lee, SeungGwan, Kang, Hee |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787735/ https://www.ncbi.nlm.nih.gov/pubmed/36556387 http://dx.doi.org/10.3390/life12122022 |
Ejemplares similares
-
NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis
por: Maeda, Shin
Publicado: (2010) -
Harmine Alleviated Sepsis-Induced Cardiac Dysfunction by Modulating Macrophage Polarization via the STAT/MAPK/NF-κB Pathway
por: Ruan, Weibin, et al.
Publicado: (2022) -
Serum NF-κBp65, TLR4 as Biomarker for Diagnosis of Preeclampsia
por: Litang, Zhao, et al.
Publicado: (2017) -
Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
por: Zhang, Kun, et al.
Publicado: (2023) -
Macrophages from Mice Administered Rhus verniciflua Stokes Extract Show Selective Anti-Inflammatory Activity
por: Kim, Bo-Geun, et al.
Publicado: (2018)