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Dose assessment of melatonin in sepsis (DAMSEL2) study: Pharmacokinetics of two doses of oral melatonin in patients with sepsis

Sepsis is defined as a dysregulated host response to infection, and high‐dose melatonin has been proposed as a treatment due to its antioxidant and anti‐inflammatory properties. However, there are no data describing the pharmacokinetics of high‐dose oral melatonin in critically ill patients. We unde...

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Detalles Bibliográficos
Autores principales: Galley, Helen F., Allen, Lee, Colin, Pieter J., Galt, Sally P., Webster, Nigel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787748/
https://www.ncbi.nlm.nih.gov/pubmed/36046952
http://dx.doi.org/10.1111/jpi.12830