Significance of Preexisting Vector Immunity and Activation of Innate Responses for Adenoviral Vector-Based Therapy

An adenoviral (AdV)-based vector system is a promising platform for vaccine development and gene therapy applications. Administration of an AdV vector elicits robust innate immunity, leading to the development of humoral and cellular immune responses against the vector and the transgene antigen, if...

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Detalles Bibliográficos
Autores principales: Wang, Wen-Chien, Sayedahmed, Ekramy E., Mittal, Suresh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787786/
https://www.ncbi.nlm.nih.gov/pubmed/36560730
http://dx.doi.org/10.3390/v14122727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787786/
https://www.ncbi.nlm.nih.gov/pubmed/36560730
http://dx.doi.org/10.3390/v14122727

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