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Calcium-Dependent Interplay of Lithium and Tricyclic Antidepressants, Amitriptyline and Desipramine, on N-methyl-D-aspartate Receptors

The facilitated activity of N-methyl-D-aspartate receptors (NMDARs) in the central and peripheral nervous systems promotes neuropathic pain. Amitriptyline (ATL) and desipramine (DES) are tricyclic antidepressants (TCAs) whose anti-NMDAR properties contribute to their analgetic effects. At therapeuti...

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Detalles Bibliográficos
Autores principales: Boikov, Sergei I., Sibarov, Dmitry A., Stepanenko, Yulia D., Karelina, Tatiana V., Antonov, Sergei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787943/
https://www.ncbi.nlm.nih.gov/pubmed/36555818
http://dx.doi.org/10.3390/ijms232416177