A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibility

INTRODUCTION: COVID-19 pandemic has been threatening public health and economic development worldwide for over two years. Compared with the original SARS-CoV-2 strain reported in 2019, the Omicron variant (B.1.1.529.1) is more transmissible. This variant has 34 mutations in its Spike protein, 15 of...

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Detalles Bibliográficos
Autores principales: Boer, Jennifer C., Pan, Qisheng, Holien, Jessica K., Nguyen, Thanh-Binh, Ascher, David B., Plebanski, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788125/
https://www.ncbi.nlm.nih.gov/pubmed/36569921
http://dx.doi.org/10.3389/fimmu.2022.954435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788125/
https://www.ncbi.nlm.nih.gov/pubmed/36569921
http://dx.doi.org/10.3389/fimmu.2022.954435

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