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Multiple Mutations Associated with Emergent Variants Can Be Detected as Low-Frequency Mutations in Early SARS-CoV-2 Pandemic Clinical Samples

Genetic analysis of intra-host viral populations provides unique insight into pre-emergent mutations that may contribute to the genotype of future variants. Clinical samples positive for SARS-CoV-2 collected in California during the first months of the pandemic were sequenced to define the dynamics...

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Detalles Bibliográficos
Autores principales: Kimbrel, Jeffrey, Moon, Joseph, Avila-Herrera, Aram, Martí, Jose Manuel, Thissen, James, Mulakken, Nisha, Sandholtz, Sarah H., Ferrell, Tyshawn, Daum, Chris, Hall, Sara, Segelke, Brent, Arrildt, Kathryn T., Messenger, Sharon, Wadford, Debra A., Jaing, Crystal, Allen, Jonathan E., Borucki, Monica K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788161/
https://www.ncbi.nlm.nih.gov/pubmed/36560780
http://dx.doi.org/10.3390/v14122775