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Formulated Phospholipids as Non-Canonical TLR4 Agonists

Immunogenic agents known as adjuvants play a critical role in many vaccine formulations. Adjuvants often signal through Toll-like receptor (TLR) pathways, including formulations in licensed vaccines that target TLR4. While TLR4 is predominantly known for responding to lipopolysaccharide (LPS), a com...

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Detalles Bibliográficos
Autores principales: Liang, Hong, Lykins, William R., Seydoux, Emilie, Guderian, Jeffrey A., Phan, Tony, Fox, Christopher B., Orr, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788208/
https://www.ncbi.nlm.nih.gov/pubmed/36559051
http://dx.doi.org/10.3390/pharmaceutics14122557