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Formulated Phospholipids as Non-Canonical TLR4 Agonists
Immunogenic agents known as adjuvants play a critical role in many vaccine formulations. Adjuvants often signal through Toll-like receptor (TLR) pathways, including formulations in licensed vaccines that target TLR4. While TLR4 is predominantly known for responding to lipopolysaccharide (LPS), a com...
Autores principales: | Liang, Hong, Lykins, William R., Seydoux, Emilie, Guderian, Jeffrey A., Phan, Tony, Fox, Christopher B., Orr, Mark T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788208/ https://www.ncbi.nlm.nih.gov/pubmed/36559051 http://dx.doi.org/10.3390/pharmaceutics14122557 |
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