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Targeted delivery of a vaccine protein to Langerhans cells in the human skin via the C‐type lectin receptor Langerin

Human skin is a preferred vaccination site as it harbors multiple dendritic cell (DC) subsets, which display distinct C‐type lectin receptors (CLR) that recognize pathogens. Antigens can be delivered to CLR by antibodies or ligands to boost antigen‐specific immune responses. This concept has been es...

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Detalles Bibliográficos
Autores principales: Bellmann, Lydia, Strandt, Helen, Zelle‐Rieser, Claudia, Ortner, Daniela, Tripp, Christoph H., Schmid, Sandra, Rühl, Julia, Cappellano, Giuseppe, Schaffenrath, Sandra, Prokopi, Anastasia, Spoeck, Sarah, Seretis, Athanasios, Del Frari, Barbara, Sigl, Stephan, Krapf, Johanna, Heufler, Christine, Keler, Tibor, Münz, Christian, Romani, Nikolaus, Stoitzner, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788233/
https://www.ncbi.nlm.nih.gov/pubmed/34932821
http://dx.doi.org/10.1002/eji.202149670