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Targeted delivery of a vaccine protein to Langerhans cells in the human skin via the C‐type lectin receptor Langerin
Human skin is a preferred vaccination site as it harbors multiple dendritic cell (DC) subsets, which display distinct C‐type lectin receptors (CLR) that recognize pathogens. Antigens can be delivered to CLR by antibodies or ligands to boost antigen‐specific immune responses. This concept has been es...
Autores principales: | Bellmann, Lydia, Strandt, Helen, Zelle‐Rieser, Claudia, Ortner, Daniela, Tripp, Christoph H., Schmid, Sandra, Rühl, Julia, Cappellano, Giuseppe, Schaffenrath, Sandra, Prokopi, Anastasia, Spoeck, Sarah, Seretis, Athanasios, Del Frari, Barbara, Sigl, Stephan, Krapf, Johanna, Heufler, Christine, Keler, Tibor, Münz, Christian, Romani, Nikolaus, Stoitzner, Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788233/ https://www.ncbi.nlm.nih.gov/pubmed/34932821 http://dx.doi.org/10.1002/eji.202149670 |
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